Viscosupplementation with Hyaluronate Acid Injection

Viscosupplementation is a procedure which targets individuals with osteaoarthiritis of the knee. It involves injecting hyaluronate acid into the knee joint. Hyaluronate acid is a naturally occurring substance found in joint fluid.

Effects of Hyaluronate Acid Injections

Immediate Effects

  • Hyaluronate acid does not have an immediate pain-relieving effect.
  • Immediately after the shot there may be a local reaction such a pain, warmth, and slight swelling. These symptoms generally do not last long and may be alleviated by applying an ice pack.
  • For the first 48 hours after the shot, excessive weightbearing on the leg such as prolonged standing, jogging, or heavy lifting should be avoided.

Long-term Effects

  • A reduction of knee pain may be observed over the course of the injections.
  • Hyaluronate acid seems to have anti-inflammatory and pain-relieving properties, and the injections may stimulate the body to produce more of its own hyaluronate acid.
  • The effects may last for several months.


If there is any swelling in the knee, Dr. Stefanides will remove the excess fluids before performing the hyaluronate acid injections. Depending on the product used, you will receive 3 to 5 shots over several weeks.